Erratum: Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment
نویسندگان
چکیده
منابع مشابه
Interferon β-1a and Atorvastatin in the Treatment of Multiple Sclerosis
Background: Statins, widely used cholesterol-lowering agents, have also been demonstrated to have anti-inflammatory and immunomdulatory effects. Objective: To evaluate the effects of atorvastatin in combination with Interferon-β in the treatment of multiple sclerosis (MS) in a randomized controlled clinical trial. Methods: Multiple sclerosis patients were randomized independently, in a double b...
متن کاملTranscriptional response to interferon beta-1a treatment in patients with secondary progressive multiple sclerosis.
BACKGROUND Interferon (IFN) beta-1a is an approved treatment for relapsing remitting multiple sclerosis (RRMS) and has been examined for use in secondary progressive multiple sclerosis (SPMS). However, no information regarding blood transcriptional changes induced by IFN treatment in SPMS patients is available. Our aim was to identify a subgroup of SPMS patients presenting a gene expression sig...
متن کاملinterferon β-1a and atorvastatin in the treatment of multiple sclerosis
background: statins, widely used cholesterol-lowering agents, have also been demonstrated to have anti-inflammatory and immunomdulatory effects. objective: to evaluate the effects of atorvastatin in combination with interferon-β in the treatment of multiple sclerosis (ms) in a randomized controlled clinical trial. methods: multiple sclerosis patients were randomized independently, in a double b...
متن کاملReview of the clinical evidence for interferon β 1a (Rebif®) in the treatment of multiple sclerosis
Interferon (INF) beta 1a 22 or 44 mug (Rebif((R))) administered s.c. 3 times a week (t.i.w) is a well established immunomodulating treatment for relapsing remitting multiple sclerosis (RRMS). This review focuses on its mechanisms of action, evidence of efficacy, safety, and tolerability. Several pharmacodynamic properties explain the immunomodulatory actions of INF beta 1a 22 or 44 mug s.c. t.i...
متن کاملResponse to interferon beta-1a treatment in African American multiple sclerosis patients.
BACKGROUND African Americans (AAs) with multiple sclerosis (MS) seem to have a more severe disease course than white Americans (WAs). To our knowledge, it is not known to what extent treatment with interferon beta-1a will effect the MS disease course within the AA population. OBJECTIVE To compare the response to treatment with interferon beta-1a between AA and WA MS patients. DESIGN This is...
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ژورنال
عنوان ژورنال: The Pharmacogenomics Journal
سال: 2011
ISSN: 1470-269X,1473-1150
DOI: 10.1038/tpj.2011.12